該基因編碼的蛋白質是白細胞介素7（IL7）的受體。這種受體的功能需要白細胞介素2受體γ鏈（il2rg），它是多種細胞因子受體（包括白細胞介素2、4、7、9和15）共有的一種γ鏈。該蛋白在淋巴細胞發育過程中對V（D）J重組起到關鍵作用。該基因的缺陷可能與嚴重聯合免疫缺陷（SCID）有關。另外，還發現了拼接轉錄變體。
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.