該基因編碼ETS家族轉錄因子。該基因的產物包含兩個功能域：一個與自身和其他蛋白質相互作用的N端尖（PNT）域和一個C端DNA結合域。小鼠基因敲除研究表明，它是造血和維持血管網發育所必需的。已知該基因參與了大量與白血病和先天性纖維肉瘤相關的染色體重排。
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.