WNT基因家族由編碼分泌信號蛋白的結構相關基因組成這些蛋白與腫瘤發生和一些發育過程有關，包括在胚胎發生過程中調節細胞命運和模式。這個基因是wnt基因家族的一員。在早幼粒細胞白血病和伯基特淋巴瘤的細胞系中強烈表達此外，它和另一個家族成員wnt6基因在結直腸癌細胞系中強烈表達。基因的過度表達可能通過激活wntβ-catenin-tcf信號通路在腫瘤發生過程中發揮關鍵作用。該基因和wnt6基因聚集在染色體2q35區。
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.