CalciumSignalingbyHBxofHepatitisBvirus
Hepatitis B is a small DNA virus that contains only 4 open reading frames in its genome. Three of these ORFs have been identified as the envelope, capsid and polymerase genes, while the function of the fourth has remained unknown until recently. The fourth reading frame has been called the X gene and produces HBx protein that is essential for viral replication in liver cells and acts broadly to activate a variety of ......閱讀全文
Calcium-Signaling-by-HBx-of-Hepatitis-B-virus
Hepatitis B is a small DNA virus that contains only 4 open reading frames in its genome. Three of these ORFs have been identified as the envelope, cap
Swine-as-a-Principal-R-e-servoir-of-Hepatitis-E-Virus-That-Infects-...2
NOTE. HEV strains with distinct nucleotide sequences were isolated from swine or humans in Huzhou City, Shanghai, and Deqing in eastern China, 2
Swine-as-a-Principal-R-e-servoir-of-Hepatitis-E-Virus-That-Infects-...1
Swine as a Principal R e servoir of Hepatitis E Virus That Infects Humans in Eastern ChinaYingjie Zheng,1,a Shengxiang Ge ,2,a Jun Zhang, 2 Qingshun G
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RSF1基因編碼的功能和結構描述
該基因編碼一種與乙型肝炎病毒X蛋白(hbx)相互作用的核蛋白,并通過hbx轉錄激活劑促進乙型肝炎病毒基因的轉錄,提示這種相互作用在病毒生命周期中的作用。該蛋白也與snf2h蛋白相互作用,形成rsf染色質重塑復合物,其中snf2h亞單位作為核小體依賴性atpase,該蛋白作為組蛋白伴侶。This ge
RSF1基因突變因子與藥物介紹
該基因編碼一種與乙型肝炎病毒X蛋白(hbx)相互作用的核蛋白,并通過hbx轉錄激活劑促進乙型肝炎病毒基因的轉錄,提示這種相互作用在病毒生命周期中的作用。該蛋白也與snf2h蛋白相互作用,形成rsf染色質重塑復合物,其中snf2h亞單位作為核小體依賴性atpase,該蛋白作為組蛋白伴侶。This ge
Mouse-hepatitis-B-virus-e-antigen,HBeAg-ELISA-Kit使用說明
Mouse hepatitis B virus e antigen,HBeAg ELISA Kit使用原理小鼠乙型肝炎e抗原(HBeAg)ELISA試劑盒貨號:FK-QZ2967規格:96T/48TMouse hepatitis B virus e antigen,HBeAg ELISA Kit
Mouse-hepatitis-B-virus-e-antigen,HBeAg-ELISA-Kit使用說明書
供應商: 上海樊克生物科技有限公司 數量: 100 規格: 96T/48T Mouse hepatitis B virus e antigen,HBeAg ELISA Kit使用原理 小鼠乙型肝炎e抗原(HBeAg)ELISA試劑盒 貨號:FK-QZ2967
Mouse-hepatitis-B-virus-e-antigen,HBeAg-ELISA-Kit使用說明書
供應商: 上海樊克生物科技有限公司 數量: 100 規格: 96T/48T Mouse hepatitis B virus e antigen,HBeAg ELISA Kit使用原理 小鼠乙型肝炎e抗原(HBeAg)ELISA試劑盒 貨號:FK-QZ2967
Mouse-hepatitis-B-virus-e-antigen,HBeAg-ELISA-Kit使用說明書
供應商: 上海樊克生物科技有限公司 數量: 100 規格: 96T/48T Mouse hepatitis B virus e antigen,HBeAg ELISA Kit使用原理 小鼠乙型肝炎e抗原(HBeAg)ELISA試劑盒 貨號:FK-QZ2967
海南醫學院李孟森再發表AFP生物學功能的重要成果
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Simplified-Calcium-Phosphate-Coprecipitation
Materials2x HEPES: 8 g NaCl, 0.105g NaHPO4, 6.5 g HEPES, H2O to 500 mL, pH 6.95 to 7.10 (try a range)2M CaCl2: store in aliquots at -20°CDNA 4 mg/mLPr
海南醫學院李孟森團隊發表封面文章:甲胎蛋白的新功能
2017年1月27日,國際著名腫瘤學雜志《International Journal of Cancer》(IF:5.531)以題為“HBx drives alpha fetoprotein expression to promote initiation of liver cancer ste
Virus-Infection-of-Fibroblasts
Procedure:?Day One?1. Plate cells in 60 mm dishes using 5 ml DMEM containing 10% Calf Serum. The protocol has worked well for NIH3T3 with 1 x 105 cell
Virus-Infection-of-Fibroblasts
Procedure:?Day One?1. Plate cells in 60 mm dishes using 5 ml DMEM containing 10% Calf Serum. The protocol has worked well for NIH3T3 with 1 x 105 cell
LentiVirus-Protocol
Lenti-Virus Protocol張端午A. For packing virus in 6-well plate: (if in 12-well plate, reduce all to 1/2)1. Mix the following plasmids in a 1.5 ml eppendo
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Calcium-Flux-Measurement-Using-Indo1
實驗概要Measure the calcium in cytosol with indo-1.主要試劑DMSO, Imonomycin, RPMI1640, PBS實驗步驟1. Dissolve the contents of 1 vial (50 μg indo-1) in 50 μl dry
Creation-and-Use-of-Infectious-Virus-Vector
Creation and use of your infectious vector:Plate 5 x 105 293T cells in 6 cm2 dishes containing 5 ml of media. (This can be scaled up if desired).The f
XC-Assay-of-MoMLV-Virus-Stocks
MaterialsWildtype MoMLV virus aliquot.? Stored at -80oC.Medium:? DMEM + 10% FBSNIH 3T3 TK- cellsXC cellsPolybrene 1000x stock = 4 mg/mL, sterile filte
南開大學Hepatology癌癥研究新成果
來自南開大學生命科學學院的研究人員在新研究中證實:乙型肝炎病毒X蛋白(hepatitis B virus X protein,HBx)通過CREB介導YAP癌基因促進了肝癌細胞生長。相關論文發表在12月的國際著名肝臟疾病雜志Hepatology上(最新影響因子11.665)上。 南開大
南開大學團隊揭示乙肝病毒轉錄復制調控新機制
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研究發現丙型肝炎病毒逃逸天然免疫反應的新機制
5月22日,國際學術期刊PLOS Pathogens 在線發表了中國科學院上海巴斯德研究所鐘勁課題組的研究論文:Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon sig
e抗原陰性慢性乙型肝炎患者血清表面抗原大蛋白水平...
e抗原陰性慢性乙型肝炎患者血清表面抗原大蛋白水平與乙肝型炎病毒DNA之間的關系??? ?我國約1/3的慢性乙型肝炎患者乙型肝炎e抗原(HBeAg)陰性,但仍然伴有高水平的乙型肝炎病毒(HBV)復制[1]。在不能進行HBV ?DNA檢測的單位,對這些患者HBV復制程度的判定難以進行。現探討HBeAg陰
WNT-Signaling-Pathway
Wnt family members are secreted glycoproteins who bind to cell surface receptors such as Frizzled. Wnt members can play a role in the expression of ma
Attenuation-of-GPCR-Signaling
The G-protein coupled receptor (GPCR) family transduces extracellular signals across the plasma membrane, activating cellular responses through a vari
TPO-Signaling-Pathway
Thrombopoietin (TPO) binds to its receptor inducing aggregation and activation. TPO signals its growth regulating effects to the cell through several
BCR-Signaling-Pathway
Significant progress has been made towards delineation of the intrinsic molecular processes that regulate B lymphocyte immune function. Recent observa